Gender specific effects on human eating have been previously reported. Here we
investigated sex-based differences in neural activation via whole-brain blood oxygen level-
dependent (BOLD) functional magnetic resonance imaging (fMRI) in response to high
energy-dense (high-ED) vs. low-ED visual and auditory food cues in obese men vs. women
in both fed and fasted states. The results show that in response to high vs. low ED foods in
the fed state, obese men (vs. women) had greater activation in brain areas associated with …